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Nesta Snider
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Alesse, an OC manufactured by Wyeth-Ayerst, has the same components. The monophasic desogestrel (150/30) and biphasic desogestrel preparations induced higher high-density lipoprotein cholesterol and apolipoprotein A-I levels than did their levonorgestrel-containing counterparts. Levlite, manufactured by Berlex Laboratories, contains 20 mcg Ethinyl Estradiol and 100 mcg Levonorgestrel. The antiatherogenic indexes (ratios of high-density lipoprotein cholesterol to low-density lipoprotein cholesterol and apolipoprotein A-I to apolipoprotein B were higher for monophasic desogestrel (150/30) and biphasic desogestrel than for comparable levonorgestrel-containing preparations. antibiotics The following preparations were studied. (1) monophasic desogestrel (150/30), (2) monophasic desogestrel (150/20, containing 20 micrograms of ethinyl estradiol instead of 30 micrograms of ethinyl estradiol, (3) biphasic desogestrel, (4) monophasic levonorgestrel (150/30), and (5) triphasic levonorgestrel. Apolipoprotein B increased in all preparations. Effects of three combined oral contraceptive preparations containing desogestrel plus ethinyl estradiol on lipid metabolism in comparison with two levonorgestrel preparations.The properties of three different desogestrel-containing combined oral contraceptive preparations on lipid metabolism antibiotics were compared with those of two levonorgestrel preparations. A pill containing 20 mcg Ethinyl Estradiol provides women with 33% less Estrogen than a 30-mcg pill. Low-density lipoprotein cholesterol levels were increased in monophasic levonorgestrel and clearly decreased in the lowest ethinyl estradiol-containing monophasic desogestrel (150/20) and biphasic desogestrel preparations. Headache, reported by 17.3% of study participants, was the most com side effect.. Berlex introduces new 20 mcg birth control pill.Another low-dose oral aegis (OC), Levlite, has received US Food and Drug Administration approval. Two other OCs--Loestrin and Mircette--contain 20 mcg Ethinyl Estradiol, but differ in their Progestin component or dose. The differences seen between the desogestrel and levonorgestrel preparations can best be explained by the lower intrinsic androgenicity of 3-keto-desogestrel (active metabolite of desogestrel) than that of levonorgestrel. Clinical trials involving 755 US women confirmed that Levlite provides high contraceptive efficacy with good cycle control. The effects of these preparations were assessed on high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, apolipoprotein A-I, apolipoprotein B, the ratio of high-density lipoprotein cholesterol to low-density lipoprotein cholesterol, and the ratio of apolipoprotein A-I to apolipoprotein B after 3 months of treatment, and the percentage changes with regard to pretreatment were calculated.
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